Kazakhstan becomes the first country outside Russia to authorize Sputnik M vaccine for adolescents

February 22, 2022

India

healthysoch

New Delhi, February 22, 2022 :

The Russian Direct Investment Fund (RDIF, Russia’s sovereign wealth fund) today announced that the Ministry of Health of the Republic of Kazakhstan has authorized the use of Sputnik M Russian vaccine for adolescents aged 12-17. Thus Kazakhstan has become the first country outside Russia to authorize the use of Sputnik M.

In contrast with some international producers offering their vaccines in the same dosage for both adults and adolescents, the Gamaleya Center has developed Sputnik M specifically for adolescents.

Sputnik M is a two-shot vaccine based on the same human adenoviral vectors platform, which is safe and has been widely studied for over 30 years. The only difference between Sputnik M and Sputnik V is a lower concentration of viral particles per dose: Sputnik M for adolescents has 5 times less concentration in comparison with the original Sputnik V in both shots.

Russian Ministry of Health registered Sputnik M on November 24, 2021 based on data from clinical trials confirming the high safety and immunogenicity profile of Sputnik M among adolescents. During the trials there were no serious adverse events registered following vaccination with Sputnik M. Current results are corresponding with those obtained during clinical trials and real-world data on Sputnik V after vaccinating adults.

Sputnik V has been authorized in 71 country with total population of over 4 billion people. It induces stronger and longer lasting immune response against COVID (including the Omicron variant) than many other vaccines, which is further strengthened by Sputnik Light booster. A unique comparative study[1] conducted at Lazzaro Spallanzani National Institute for Infectious Diseases in Italy by a team of 12 Italian and 9 Russian scientists has shown that Sputnik V vaccine demonstrates more than 2 times higher titers of virus neutralizing antibodies to Omicron (B.1.1.529) variant than 2 doses of Pfizer vaccine (2.1 times higher in total and 2.6 times higher 3 months after vaccination).

The study was conducted in the equal laboratory conditions on comparable sera samples from individuals vaccinated with Sputnik V and Pfizer with a similar level of IgG antibodies and virus neutralizing activity (VNA) against Wuhan variant. Sputnik V showed significantly smaller (2.6 times) reduction of virus neutralizing activity against Omicron as compared to reference Wuhan variant than Pfizer vaccine (8.1-fold reduction for Sputnik V in contrast to 21.4-fold reduction for Pfizer vaccine).

Based on the data collected by the Spallanzani Institute and results of Gamaleya Center’s studies Sputnik V provides for strong immune response against Omicron, which is further strengthened by boosting with one-shot Sputnik Light vaccine (the first component of Sputnik V).

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Health Tips

Dr. T S Kler Padma Bhushan Awardee
MD, DM, MRCP, FRCP(U.K), FACC, D.Sc
Chairman – Fortis Heart Institute Gurugram

Precautions to avoid Corona Virus:

  1. Stay home as far as possible.
  2. Wash hands with soap and water frequently.
  3. Keep distance from people even your home members.
  4. Keep atleast 1-2 metres away from anybody coughing.
  5. Don’t touch your face, nose and mouth.

 

Dr. K.K Says

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