Rare cases of Mucormycosis of small intestine seen at Sir Ganga Ram Hospital

May 22, 2021

Black fungus of INTESTINE: Novel complication of pandemic

India

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New Delhi, May 22, 2021 ;

Kumar (56 year old) resident of Delhi, lost his 3 of his family members including his wife due to COVID.  He had barely completed the last rites of his wife when he experienced pain in his abdomen. He had been tested positive for COVID along with his wife and had been experiencing mild covid symptoms initially. His abdominal pain was considered gastritis/ stress related and self medication for acidity was taken which delayed  proper treatment by 3 days.

He was finally evaluated in COVID emergency of  Sir Ganga Ram Hospital by Dr Ushast Dhir, senior consultant in department of Surgical Gastroenterology and Liver Transplantation. The CT scan revealed his small intestine (jejunum) had perforated. His COVID disease also had worsened by now requiring ventilator support. The patient was admitted and taken up  urgently for surgery.

According to Dr Dhir ,”Ulceration  of Jejunam  (First part of Small Intestine) in the patient raised my suspicion of fungal disease and patient was  immediately started on antifungal treatment . We sent the portion of removed intestine for Biopsy.”

The family of Mr Ijaz,  68 year old was cheered up to know that their father had recovered from  COVID. But he started having mild abdominal pain. He was a diabetic and had received steroids for treatment of COVID. The patient had no associated fever and pain was very mild. His clinical examination also did not show any signs of intestinal perforation.But,high index of suspicion lead Dr Piyush Ranjan, senior consultant of Medical Gastroenterology at Sir Ganga Ram Hospital New Delhi, to get an urgent CT for the patient. The CT scan revealed small intestinal perforation similar to the first one. 

The biopsy confirmed our worst fear of  Mucormycosis of small intestine in both patients  . Both these patients had COVID and had diabetes but  only one of them had received steroids.

Both these patients were operated by  Dr Ushast Dhir, who revealed that these patient had similar intra-operative findings where first part of  small intestine(jejunum) had outpouchings called diverticula and these diverticula had perforated along with surrounding ulceration.

Mucormycosis most commonly involves Rhino-orbital-cerebral  system or the lungs.Intestinal or GI mucormycosis is very rare disease and  most commonly involves stomach or large intestine. These patients in majority are immune-compromised. Majority of gastro-intestinal mucormycosis is seen in  organ transplant recipients. The cases treated at Sir ganga ram hospital were unique as as they had covid and small intestine (instead of stomach /colon)was involved in both.

GI mucormycosis is rare and the patient presents with vague abdominal symptoms. In recent times history of COVID exposure along with treatment with steroids should warrant an early CT scan of abdomen.

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Health Tips

Dr. T S Kler Padma Bhushan Awardee
MD, DM, MRCP, FRCP(U.K), FACC, D.Sc
Chairman – Fortis Heart Institute Gurugram

Precautions to avoid Corona Virus:

  1. Stay home as far as possible.
  2. Wash hands with soap and water frequently.
  3. Keep distance from people even your home members.
  4. Keep atleast 1-2 metres away from anybody coughing.
  5. Don’t touch your face, nose and mouth.

 

Dr. K.K Says

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