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Morning Health Talk :
New Delhi, June 07, 2018 :
Clinical
- Babies born with diabetes can now be treated successfully with oral sulphonylurea tablets instead of insulin injections. Researchers from the University of Exeter have collaborated with groups in Norway, Italy, France and Poland to analyse findings from 81 patients from 20 different countries. The results showed they were successfully treated through sulphonylurea tablets and had excellent blood sugar control over the long-term. Neonatal diabetes is diagnosed before the age of six months and in half of all cases is caused by a mutation in their KCNJ11 gene, which is involved in keeping insulin-producing cells in the pancreas working properly. This results in life-threatening diabetes soon after birth.
- Lasix vs Dytor: Studies in subjects with normal renal function indicate that a diuresis begins with as little as 10 mg of furosemide, with the maximal effect being seen with 40 mg given intravenously. If furosemide is given orally, this maximum dose is usually twice the intravenous dose (80 mg) since its bioavailability is only about 50 percent. The equivalent maximal dose is 15 to 20 mg for either oral or intravenous torsemide since this is almost completely absorbed. All of the loop diuretics produce the same response if given at equipotent doses. Going above these maximum doses will produce little or no further diuresis but may increase the risk of side effects.
Legal
- A 3-year-old Missouri girl has reached a $1,375,000 settlement with health-care providers whom she alleged failed to spot dehydration in the days following her birth, leading to a brain injury. Her attorney, Mike Meyer of Bartimus Frickleton Robertson Rader in Leawood, Kansas, said the parties, whose identities remain confidential as part of the settlement agreement
Dr KK Aggarwal
Padma Shri Awardee
Vice President CMAAO
President HCFI
